Neurorehabilitation for Parkinson’s disease: Can remote rsEEG be used as a valid predictive measure of short term plasticity?
From ANT Neuro Educational Webinar Series
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Welcome to ANT Neuro Educational Webinar Series!
Parkinson's disease (PD) is a progressive neurodegenerative disorder with no cure and few treatments can alter its progression. Exercise with dance and music, with virtual or onsite participation, improves motor (Hackney et al 2006), and nonmotor symptoms (Westheimer 2008) as well as mood (Fontanesi & DeSouza 2021; Ghanai et al 2021). Preliminary evidence from our lab has revealed a slowing of typical PD progression related to dance class participation (Bearss & DeSouza, 2021). Utilizing modelling of behavioral and neuroimaging data we will now display rsEEG alpha rhythm brain changes after participation in a single 75-minute dance class using the EMOTIV EPOC 14-channel cap (Levkov 2015; Bearss 2021). Our longitudinal study suggested disease motor and nonmotor symptom progression is reduced for weekly dance participants (n = 16 PD) compared to the Michael J. Fox Foundation (PPMI) reference data (n = 16) (Bearss & DeSouza 2021). Additionally, rsEEG alpha rhythm change has been observed over the 3-year research study period. Lastly, I will touch on a paper examining this PPMI longitudinal data, where we provide evidence of which measures are consistently (cross-validated by five models) most predictive of PD (Leger, Herbert & DeSouza 2020). The key aim of this work is to be able to model our behavioural and rsEEG data to identify biomarkers of neurodegenerative disease.
This research will be presented by Dr. Joseph DeSouza who is an associate professor of Systems Neuroscience at York University. His specific research interests lie within the realms of converting multisensory signals of vision, audition and touch into motor movements of the eyes, hand & body and how these mechanisms are modulated by various mechanisms of short and long term cognitive control, attention and suppression.
We look forward to welcoming you to this webinar!
ANT Neuro organization team
[event ID: 4778]
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